(HFA-134a pharm) Pharmaceutical Excipients Tetrafluoroethane
C2H2F4
CAS No.：811-97-2|
Item |
Technical Index |
|
Appearance |
Colorless, transparent, clear |
|
Identification |
Infrared spectrum conform to requirement |
|
Boiling point |
-26℃ + 0.5℃ |
|
Purity, % ≥ |
99.99 |
|
Moisture,% ≤ |
0.0010 |
|
Acidity (as HCl), % ≤ |
0.0001 |
|
Non-volatile residue, % ≤ |
0.0010 |
|
Chlorides(Cl-) |
Pass |
|
Volume fraction of non-condensable gas (25℃), % （v/v） ≤ |
1.5 |
|
Organic impurities |
|
|
CFC-12, % ≤ |
0.0003 |
|
HFC-143a, % ≤ |
0.0002 |
|
HFC-32,% ≤ |
0.0003 |
|
CFC-114a, % ≤ |
0.0003 |
|
CFC-114, % ≤ |
0.0003 |
|
HFC-125, % ≤ |
0.0003 |
|
HCFC-1131, % ≤ |
0.0010 |
|
HCFC-124, % ≤ |
0.0003 |
|
HFC-134, % ≤ |
0.0090 |
|
HCFC-133a, % ≤ |
0.0003 |
|
CFC-113a, % ≤ |
0.0003 |
|
Total unsaturated matter, % ≤ |
0.0020 |
|
Total unknown impurities, % ≤ |
0.0010 |
• Under normal temperature and pressure, the product is a colorless gas with slight scent of ether;
• Melting point: -103.15℃, boiling point: -26.1℃, liquid density: 1.206 g/cm3(25℃);
• Under normal condition, it is compressed into liquid and stored in steel cylinder, its thermodynamic property is as similar as that of CFC-12;
• ODP value: 0, GWP value: 1200.
• 1,1,1,2-tetrafluoroethane is a main alternative for CFCs propellant;
• In addition, due to its low toxicity and non-flammability, it is developed into carrier for pharm inhalant (i.e. pharm aerosol), like anti-asthma aerosol, to treat asthma, COPD (Chronic obstructive pulmonary desease);
• It also could be used in Nasal Aerosol and foam aerosol to treat irritable rhinitis;
• Its another use is in mouth and local aerosol (to improve nerve sensitivity, strength tooth dynamic and relieve pain, etc.)
• Refillable cylinder: 400L, 800l, 926L, 1000L;
• ISO tank;
• The product is packaged in appropriate cylinders or tanks. It should be kept in cool and dry place, without being exposed to heat source, sunlight and rain;
• Transportation should comply with the Chinese railway and road transportation regulation concerning hazardous cargo.